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nt will become default BLAST db

Starting November 26, 2012, the nucleotide collection (nt) will be the default nucleotide search database.  The nucleotide collection consists of GenBank+EMBL+DDBJ+PDB+RefSeq sequences, but excludes...

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Improved BLAST statistics described in BMC Research Notes.

BLAST calculates expect values that describe the significance of a match, with a lower expect value indicating a more significant match. Since the 2.2.26+ release, BLAST+ uses an improved method to...

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Microbial BLAST improved

New and more effective search options are now available.     For pages with nucleotide search sets (i.e., BLASTN and TBLASTN), Microbial BLAST now allows users to choose between "Representative...

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BLAST 2.2.28+ released

A new version of the stand-alone BLAST applications is available.      This release includes a number of improvements as well as a large number of bug fixes.  See the BLAST+ user manual for details on...

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New NAR article on the BLAST report

A new article, "BLAST, a more efficient report with usability improvement", is now available.   The article is available through http://www.ncbi.nlm.nih.gov/pubmed/23609542 and discusses the redesigned...

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NAR article describes IgBLAST

A new article, "IgBLAST: an immunoglobulin variable domain sequence analysis tool", is now available.  The article is available through http://www.ncbi.nlm.nih.gov/pubmed/23671333 and discusses the...

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Update to SRA-BLAST

SRA-BLAST has undergone a dramatic update, both in terms of user interface and search performance.   SRA-BLAST now includes:   * Targeted searching within one or more SRA Experiment sets (i.e., "SRX...

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Update to organism BLAST databases

The organism BLAST pages are being updated to use top-level (chromosome + unplaced and unlocalized scaffolds) RefSeq genomic records instead of scaffold records. This change has also been made for the...

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BLAST 2.2.29+ released

A new version of the stand-alone BLAST+ applications is available. This release includes a number of improvements as well as a large number of bug fixes. The BLAST+ applications may be downloaded here....

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BLAST XML

Changes to the BLAST XML have been proposed.      You may read and comment about the proposed changes at this link.

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Custom BLAST databases

Create custom BLAST databases with entrez.     A new video describes the creation of custom databases with an entrez query.  The NCBI new item about this video is here.  

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BLAST in the Cloud

The NCBI now provides an experimental BLAST installation hosted at Amazon Web Services. BLAST is provided as an Amazon Machine Image that allows users to run stand-alone searches with the BLAST+...

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BLAST in the Cloud Webinar, July 30th, 3:00 PM

​The NCBI now provides an experimental BLAST installation hosted at Amazon Web Services. This presentation shows you how to use the experimental NCBI-BLAST Amazon Machine Image(AMI) to configure...

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New gap costs available for PAM30 and PAM70

The BLAST webpage now offers additional, more stringent, gap costs for PAM30 and PAM70.  These gap costs may produce better alignments for closely related sequences.  Try out more stringent costs with...

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Find Genomic BLAST pages

​You can now find Genomic BLAST pages using the search box from the BLAST homepage.  Simply start typing your organism into the box and suggestions will appear.  Once you select a suggestion, you will...

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BLAST 2.2.30+ released

​A new version (2.2.30) of the stand-alone BLAST executables is now available.  There are a number of improvements in the 2.2.30 release. These improvements include new tasks for BLASTX and TBLASTN...

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PDB and Swiss-Prot on the FTP site

The NCBI is now distributing the BLAST databases for protein PDB (pdbaa) and Swiss-Prot (swissprot) as stand-alone BLAST databases, rather than as subsets of the non-redundant (nr) database.  This...

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Webinar: The Statistics of Local Pairwise Sequence Alignment, Parts 1 and 2.

On Thursday, January 22nd, Stephen Altschul of NCBI will present the first part of a discussion of the statistical theory for local sequence alignments like those produced by the BLAST database search...

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MOLE-BLAST

​MOLE-BLAST is a new tool to classify multiple query sequences and discover their relationship to each other. This tool provides a taxonomic context for the queries. It is intended to work with a...

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BLAST XML

​The NCBI is now making a new version of the BLAST XML available for testing.  Read about the changes and how to access BLAST results using the new XML here.

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