BLAST 2.2.30+ released
A new version (2.2.30) of the stand-alone BLAST executables is now available. There are a number of improvements in the 2.2.30 release. These improvements include new tasks for BLASTX and TBLASTN...
View ArticlePDB and Swiss-Prot on the FTP site
The NCBI is now distributing the BLAST databases for protein PDB (pdbaa) and Swiss-Prot (swissprot) as stand-alone BLAST databases, rather than as subsets of the non-redundant (nr) database. This...
View ArticleWebinar: The Statistics of Local Pairwise Sequence Alignment, Parts 1 and 2.
On Thursday, January 22nd, Stephen Altschul of NCBI will present the first part of a discussion of the statistical theory for local sequence alignments like those produced by the BLAST database search...
View ArticleMOLE-BLAST
MOLE-BLAST is a new tool to classify multiple query sequences and discover their relationship to each other. This tool provides a taxonomic context for the queries. It is intended to work with a...
View ArticleBLAST XML
The NCBI is now making a new version of the BLAST XML available for testing. Read about the changes and how to access BLAST results using the new XML here.
View ArticleBLAST 2.2.31+ released
A new version (2.2.31) of the stand-alone BLAST+ executables is now available. This release includes the new and improved XML and JSON. Additonally there are a number of other improvements and bug...
View ArticleBLAST XML
The BLAST+ 2.2.31 executables can produce a new version of the BLAST XML (XML2). XML2 is also also available from the NCBI BLAST website and the BLAST AMI at the AWS marketplace. XML2 is an update...
View ArticleSmartBLAST
Use SmartBLAST for faster BLASTp searches with a graphical view. Read about SmartBLAST at the NCBI Insights blog or just try it at http://blast.ncbi.nlm.nih.gov/smartblast/
View ArticleBLAST+ 2.3.0 released
A new version (2.3.0) of the stand-alone BLAST+ executables is now available. This new version includes a beta release of SAM format as well as support for single-file mode for the BLAST XML2 and...
View ArticleSearching Whole Genome Shotgun sequences
It is now much easier to search WGS (Whole Genome Shotgun) with stand-alone BLAST on your own computer. New tools from the NCBI allow you to BLAST just the WGS projects you are interested in. You can...
View ArticleNew BLAST home page preview.
The new design provides improved navigation, a cleaner look, and easier access to new BLAST services. Read more about the new home page here.See the preview page here.
View ArticleBLAST+ 2.4.0 released
A new version (2.4.0) of the BLAST+ executables is now available.The new version offers improved scoring for selenocysteine residues in the query and database sequences. It also improves performance...
View ArticleBLAST and HTTPS
The BLAST URL API is moving to HTTPS. On September 30, 2016, the NCBI will move to HTTPS. Applications using the BLAST URL API without HTTPS may stop working. For more details, please read this...
View ArticleIntroducing: Magic-BLAST
Magic-BLAST is a new tool for mapping large sets of next-generation RNA or DNA sequencing runs against a whole genome or transcriptome. Magic-BLAST optimizes a composite score for each alignment,...
View ArticleBLAST+ 2.5.0 released
A new version (2.5.0) of the BLAST+ executables is now available. The new version offers support for HTTPS, accession.version as the primary sequence identifier, support for composition-based...
View ArticleOctober 11th NCBI Minute
BLAST+ 2.5.0 with Support for HTTPS,accession.version Identifiers and Much More On October 11th, the NCBI Minute will be a discussion of changes made to the BLAST standalone distribution due to the...
View ArticleHTTPS and BLAST API calls
BLAST API calls must use HTTPS by November 9, 2016. For more information, please see https://www.ncbi.nlm.nih.gov/news/07-27-2016-new-guidance-https/
View ArticleMagic-BLAST 1.1.0 available
The new version offers support for HTTPS, accession.version as the primary sequence identifier, and fixes problems with SAM flag values. The release notes are at...
View ArticleBLAST+ 2.6.0 released
A new version (2.6.0) of the BLAST+ executables is now available. This new version offers improved support for use of accession.version as the primary NCBI identifier. The speed of blastdbcmd when...
View ArticleMagic-BLAST 1.2.0 released
A new version of the BLAST mapping tool is now available.The new version handles multiple SRA accessions, offers improved splice site detection and multi-threading performance, and fixes issues with...
View ArticleQuickBLASTP
Try QuickBLASTP for a fast protein search of nr.Read about QuickBLASTP at the NCBI Insights blog or just try it here.
View ArticleMagic-BLAST 1.3.0 released
A new version (1.3.0) of the BLAST RNA-seq mapping tool, Magic-BLAST, is now available. The new version provides improved sensitivity, reports unaligned reads, does not cache SRA sequences in local...
View ArticleBLAST+ 2.7.1 released
A new version (2.7.1) of the BLAST+ executables is now available.In this new version, blastdbcmd can look up taxonomic names (e.g., scientific or common name) faster. We have also made some low-level...
View ArticleIgBLAST 1.8.0 released
A new version of IgBLAST is now available. This release has the following improvements:The igblastn executable can now multi-thread much more efficiently for large sets of queries. The default number...
View ArticleQuickBLASTP webinar
The QuickBLASTP webinar is now available on YouTube. You can access the video of the webinar (from January 10, 2018) at https://youtu.be/pO_a4e7QGRkQuickBLASTP is a new way to search large sets of...
View ArticleBLAST+ 2.8.0-alpha released
BLAST+ now has a better database.We have made some recent enhancement to the BLAST+ applications that allow you to:1.) Limit your search by taxonomy using information built into the BLAST...
View ArticleMay 16 webinar
Improved BLAST+ and BLAST databases: now with taxonomic information.Find out about easier taxonomic limits in the latest BLAST+ release. Read more and sign up at...
View ArticleIgBLAST 1.9.0 released
IgBLAST now supports AIRR rearrangement reports.With an increasing amount of repertoire studies using next generation sequencing (NGS) technology to generate very large sets of Ig/TCR rearrangement...
View ArticleGetting the Genomic Context for BLAST Protein Matches
Do you ever want to see the flanking genes of a protein match from a BLAST search? A webinar on June 20 will teach you how to find this information. Read more and sign up at:...
View ArticleIntroducing the BLAST widget - integrating your BLAST results into NCBI’s...
Wantto analyze your BLAST results in the context of a genome browser and comparethose results against other genome assembly annotations? Introducing the GenomeData Viewer (GDV) and the BLAST widget.We...
View ArticleFive Teaching Examples on how to use NCBI BLAST.
Learn how to easily incorporate BLAST into your undergraduate biology courses with cut and paste examples. Webinar to be held on July 25, 2018 at 12 noon EDT.Sequence similarity search tools such as...
View ArticleIntroducing the BLAST widget - integrating your BLAST results into NCBI’s...
Want to analyze your BLAST results in the context of a genome browser and compare those results against other genome assembly annotations? Introducing the Genome Data Viewer (GDV) and the BLAST...
View ArticleA new version (1.4.0) of the BLAST RNA-seq mapping tool, Magic-BLAST, is now...
Magic-BLAST version 1.4.0 is released. The new version provides an option for strand-specific alignments, improved mapping sensitivity, better alignments in presence of higher sequencing error rates,...
View ArticleUsing BLAST Well, How to Maximize Your Search Efforts: Webinar on October 3,...
In this webinar, the NCBI BLAST team lead will show you how to be more effective with BLAST. You will learn how to:Choose the most appropriate BLAST databases based on size and contenSelect and...
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Learn how to use BLAST
See our collection of webinars and tutorials designed to help you Examples are:• Improved standalone BLAST database and programs: now with taxonomic information• Getting the most out of Web BLAST...
View ArticleIgBLAST version 1.12 available
IgBLAST facilitates the analysis of immunoglobulin and T cell receptor variable domain sequences.The new version increases the allowed distance between V gene end and J gene start positions (from 90 bp...
View ArticleBLAST+ 2.8.1 is released
New databases, better performance. This is the first production release to support the new BLAST database version (BLASTDBv5). This is a taxonomically aware version of the BLAST database that:1.)...
View ArticleUnderstanding BLAST+ parameters
Having a basic understanding of BLAST+ parameters is essential to getting the results that meet your needs. A recent Bioinformatics letter(external link) clears up some confusion and...
View ArticleAre you identifying organisms? The 16S database may be your best choice.
For initial searches, the 16S database contains the data that most people need to identify organisms.Using the 16S database will speed up your searches and provide you the results that you are most...
View ArticleA new version IgBLAST (1.13) is here.
Your tool to facilitate the analysis of immunoglobulin and T cell receptor variable domain sequences. The new version of IgBLAST is now available with three new features:Determining the V gene...
View ArticleBLAST+ 2.9.0 is here.
BLAST+ 2.9.0 is released - enhanced support for the new database format.This version enhances support for the new BLAST database version (BLASTDBv5). This includes:1.) Support for the RCSB Protein...
View ArticleNew BLAST Results Page in Beta
A user driven experiment to improve the BLAST solution. The design of this new Results page is based on feedback and interviews, and the goal is better usability and an attempt to better expose...
View ArticleWebinar on May 15, 2019
Using organism (taxonomy) information in your BLAST search.Limiting a BLAST search to particular organism or group is important for efficient BLAST searches and results that are easier to interpret...
View ArticleA new version IgBLAST (1.14.0) is here.
We’ve released a new version of IgBLAST with three new improvements. The new version of IgBLAST is now available with three new features:Implementation of AIRR format is more consistent with AIRR...
View ArticleNew BLAST Results to become default on Aug 1, 2019
To help instructors integrate the new design into their lesson plans, we are making the change before the fall semester. The new BLAST results page that has been available for testing since April...
View ArticleThe BLAST programs and databases are now cloud ready
NCBI now provides a dockerized version of BLAST that you can use on the cloud.BLAST workloads often come in bursts. You may want to search a large number of sequences all at once and need the results...
View ArticleNew BLAST Results is now the default view
Based on user feedback the New Results page is an overwhelming success. The new BLAST results page that has been available for testing since April is now the default results page. Thank you for your...
View ArticleNew nr database available with fewer redundant titles
We have made changes to the nr version 5 database, (nr_v5), to facilitate better search results and improved performance.We have reduced the number of redundant titles in the nr_v5 database used by...
View ArticleA New version of Magic-BLAST(1.5.0) is here.
The BLAST tool for mapping large next-generation RNA or DNA sequencing runs against a whole genome or transcriptome. Magic-BLAST, the BLAST tool that aligns next generation sequencing reads, has just...
View ArticleEnd of updates for BLAST+ version 4 databases (dbV4)
Start moving to the new version 5 databases!We recently updated the version 5 BLAST protein and nucleotide databases, (dbV5), on our FTP site to be accession-based. As we described in a previous...
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