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BLAST 2.2.21 now available

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This release includes new BLAST+ command-line applications.

 

The BLAST+ applications have a number of advantages over the older applications that include working more robustly with long sequences and a new type of masking (database masking).  For details see ftp://ftp.ncbi.nlm.nih.gov/blast/executables/blast+/LATEST/user_manual.pdf.  The new applications can be downloaded from ftp://ftp.ncbi.nlm.nih.gov/blast/executables/blast+/LATEST  These applications have been built with the NCBI C++ toolkit. Changes from the last release are listed below.

 

The older C toolkit applications (e.g., blastall) are still available at ftp://ftp.ncbi.nlm.nih.gov/blast/executables/release/2.2.21/

Changes from the last release are listed below.

 

Please send questions or comments to blast-help@ncbi.nlm.nih.gov

 

 

 

c toolkit binary changes:

* corrected a bug in xml output (SB-217)

* corrected a bug with query concatenation in ungapped searches (SB-263)

* tabular output header for "-m 8" now printed even if there are no results. (sb-290)

 

C++ toolkit binary improvements:

* best hit algorithm, see section 4.5.12 in ftp://ftp.ncbi.nih.gov/blast/executables/blast+/LATEST/user_manual.pdf

* improve culling option performance

* fix mutex problems in BLAST database reader.

* improve performance of database masking option.

 

C++ binary changes:

* database masking enabled, see details in ftp://ftp.ncbi.nih.gov/blast/executables/blast+/LATEST/user_manual.pdf

* makeblastdb user-interface improvements

* blastdbcmd can now emit masked fasta for a masked database


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